Creating a New Generation of Solutions for Your Skin

Our Programs

Therapeutics

Program
Therapeutic Area
Candidate
IND-enabling
Ph1
Ph2
Ph3
RLX-202
Dermatology
Candidate
RLX-202
Therapeutic Area:
Dermatology
Phase:
Candidate
RLX-202
Aesthetic Dermatology
Candidate
RLX-202
Therapeutic Area:
Aesthetic Dermatology
Phase:
Candidate

Professional Skincare

Product
Development
Clinical Trial
Launched
Longevity Face Serum
Clinical Trial
Longevity Face Serum
Phase:
Clinical Trial

RLX-202

MOA: selective mTORC1 inhibitor

Tx Area: Dermatology

A Multifunctional Strategy for Chronic Skin Disorders

In skin, TORC1 plays a key role in skin barrier function, neurovascular sensitivity, sebaceous and follicular activity, and immune modulation. Rapalogix is developing a family of chemically novel TORC1 inhibitors positioned to address multiple drivers of chronic skin disorders beyond just inflammation.

Our lead program is RLX-202—a highly selective TORC1 inhibitor engineered for optimal skin penetration and targeted activity. RLX-202 is in development for chronic skin diseases with underlying TORC1 dysfunction.

Optimizing Skin Beyond the Mirror

Rooted in longevity science.  Proven in skin.

Our professional skincare line is powered by our proprietary technology RLX-201—a cosmetic longevity molecule designed to reset skin’s cellular balance for long-term health and resilience.

Our first product represents a new class of pro-longevity professional skincare. Formulated to calm overactive pathways and support skin renewal, RLX-201 delivers visible results at the surface and measurable changes at the cellular level.

Re-Q HealthTM Pro-Longevity Skincare Coming Soon!

Professional Skincare Line

Professional Skincare Line

Skin Health Technologies

Professional Skincare Line

Advancing the Future of Skin Longevity Measurement

In collaboration with innovators in AI-powered skin analysis and molecular diagnostics, Rapalogix is developing next-generation tools to assess skin health. In combination, these technologies will deliver a comprehensive view of skin function, age, and resilience over time.

Currently in clinical testing alongside our cosmetic product, these platforms represent the next leap forward in pro-longevity care.

Why Cellular Longevity Is the Future of Skincare >
Healthy Fibroblast
  • Efficient energy production thanks to functional mitochondria.
  • Proper protein and molecule processing via the Golgi apparatus and ER.
  • Intact genetic material allows cells to divide and repair properly.
  • Autophagy (the cell’s recycling system) is working well helping clean up waste
Learn more about Fibroblast
Exhausted (Aged) Fibroblast
  • Damaged mitochondria = low energy.
  • Altered DNA = higher risk of errors and dysfunction.
  • Dysfunctional Golgi and ER = poor protein handling and transport.
  • Inefficient autophagy = buildup of cellular waste
Learn more about Fibroblast

Healthy Skin Begins with Healthy Cells

Whether you’re managing the signs of aging or navigating chronic conditions like rosacea or psoriasis, one truth remains: healthy skin depends on healthy cells. In their optimal state, skin cells self-repair DNA, remove internal damage through autophagy, regulate inflammation, and produce key structural proteins like collagen and elastin. When these processes break down, the result is visible aging—and in many cases, chronic skin disorders.

Healthy skin cells are capable of:
  • Self-repair (DNA repair and protein folding)
  • Autophagy and apoptosis to remove damage
  • Extracellular matrix maintenance
  • Inflammatory response regulation
  • Controlled replication and regeneration

Burden of Overstimulation of Cells

Most anti-aging and therapeutic treatments—including retinoids, lasers, peptides, and even some biologics—work by stimulating skin activity. While they may deliver short-term results, chronic overstimulation can exhaust cellular resources, impair healing, disrupt the skin barrier, and even exacerbate inflammation—particularly in sensitive or inflammatory conditions like rosacea and psoriasis.

OVERstimULAtion can cause cell damage:
  • Chronic overstimulation exhausts fibroblasts
  • Reduces regenerative skin capacity
  • Promotes cellular senescence
  • Accelerates aging-like skin changes
  • Overactive cell turnover compromises skin barrier
  • Leads to dryness, scaling, and irritation
  • Increases susceptibility to environmental irritants

Advancing the Future of Skin Longevity Measurement

In collaboration with innovators in AI-powered skin analysis and molecular diagnostics, Rapalogix is developing next-generation tools to assess skin health. In combination, these technologies will deliver a comprehensive view of skin function, age, and resilience over time.

Currently in clinical testing alongside our cosmetic product, these platforms represent the next leap forward in pro-longevity care.

Why Cellular Longevity Is the Future of Skincare >

Skin Health Technologies

Professional Skincare Line
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